Endocrine Abstracts

Background: Diagnosis of secondary adrenal insufficiency (SAI) during pregnancy is challenging due to physiological adaptations and progressive increase of cortisol level throughout the pregnancy (1). The 250-mg standard ACTH stimulation test (CST) is recommended for evaluation of adrenal hypofunction in pregnancy however, measurement of serum cortisol (SC) maybe misleading in patients with partial SAI. Furthermore, utility of salivary free cortisol (SaFC) (2) and serum DHEA-s...